We are seeking a Senior Scientist to lead our In Vivo Biology group who will be responsible for in vivo oncology and immunology models and pharmacokinetics for the characterization of immuno-oncology focused protein therapeutics.

Responsibilities:

  • Work with Project Teams, and the Immunology and Assay groups to identify the appropriate in vivo tumor and autoimmunity models for testing safety and efficacy of Akriveia’s protein therapeutics
  • Qualify and perform in vivo models, and analyze the data with the appropriate statistical analyses
  • Oversee husbandry of mice and meet all guidelines set forth in the NIH “Guide for the Care and Use of Laboratory Animals”
  • Work with CROs, collaborators and partners to transfer test materials, samples, data, and protocols for animal models into, or out of, Akriveia, as appropriate
  • Identify and integrate technologies that improve or expand the ability to assess molecules in vivo by working with teammates, collaborators, vendors, and staying abreast of the literature
  • Enter all data into laboratory notebooks and databases on a daily basis and ensure staff members do so, approve weekly progress reports from staff, and generate weekly summary reports for management
  • Regular participation and presentation at Project Team and departmental meetings
  • Provide proper training of staff and continue to explore opportunities to expand their responsibilities and capabilities

Qualifications:

  • Ph.D., post-doctoral experience and +3 years in the field of immuno-oncology, or other relevant fields; ideally, with 2+ years’ experience working in a CRO, biotechnology or pharmaceutical company
  • Technical experience with development, qualification, and execution syngeneic tumor models, as well as PDX and/or humanized tumor models, and IACUC documentation
  • Experience with any of the following is desirable: running a small animal facility, pharmacokinetic analyses, animal models of autoimmunity, or assessments such as ELISA, FACS, and IHC
  • Experience managing staff is a plus
  • A track record of innovation and scientific rigor, strong problem solving and troubleshooting skills, and ability to contribute constructively to discussions
  • Goal oriented, organized, capable of prioritizing and working on multiple projects, and able to execute to timelines that meet company goals
  • Work well in a cross functional team environment, both independently as well as be willing to help others
  • Excellent verbal and written communication skills
  • Driven by a desire to create the next generation of immunotherapy based cancer therapeutics and the vision to offer cancer patients efficacious and tolerable new therapies that extend and improve their lives

We offer:

  • The opportunity to work in an innovation driven, exciting biotechnology company doing ground-breaking work in the field of immuno-oncology
  • The opportunity to work within and have a significant impact on a highly motivated team of like-minded people
  • Highly competitive compensation package including a base salary, annual bonus potential, stock options, 401k, healthcare benefits and paid time-off
  • This is a full-time position in the Cambridge, MA area

To apply for this position, please complete the following:

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